Vector Choice Determines Immunogenicity and Potency of Genetic Vaccines against Angola Marburg Virus in Nonhuman Primates

The immunogenicity and durability of genetic vaccines are influenced by the composition of gene inserts and choice of delivery vector. DNA vectors are a promising vaccine approach showing efficacy when combined in prime-boost regimens with recombinant protein or viral vectors, but they have shown li...

Full description

Saved in:
Bibliographic Details
Main Authors: Geisbert, Thomas W., Bailey, Michael, Geisbert, Joan B., Asiedu, Clement, Roederer, Mario, Grazia-Pau, Maria, Custers, Jerome, Jahrling, Peter, Goudsmit, Jaap, Koup, Richard, Sullivan, Nancy J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937810/
https://ncbi.nlm.nih.gov/pubmed/20660192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00594-10
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items