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Vector Choice Determines Immunogenicity and Potency of Genetic Vaccines against Angola Marburg Virus in Nonhuman Primates

The immunogenicity and durability of genetic vaccines are influenced by the composition of gene inserts and choice of delivery vector. DNA vectors are a promising vaccine approach showing efficacy when combined in prime-boost regimens with recombinant protein or viral vectors, but they have shown li...

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Autors principals: Geisbert, Thomas W., Bailey, Michael, Geisbert, Joan B., Asiedu, Clement, Roederer, Mario, Grazia-Pau, Maria, Custers, Jerome, Jahrling, Peter, Goudsmit, Jaap, Koup, Richard, Sullivan, Nancy J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937810/
https://ncbi.nlm.nih.gov/pubmed/20660192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00594-10
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