Immune Protection of Nonhuman Primates against Ebola Virus with Single Low-Dose Adenovirus Vectors Encoding Modified GPs

BACKGROUND: Ebola virus causes a hemorrhagic fever syndrome that is associated with high mortality in humans. In the absence of effective therapies for Ebola virus infection, the development of a vaccine becomes an important strategy to contain outbreaks. Immunization with DNA and/or replication-def...

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Main Authors: Sullivan, Nancy J, Geisbert, Thomas W, Geisbert, Joan B, Shedlock, Devon J, Xu, Ling, Lamoreaux, Laurie, Custers, Jerome H. H. V, Popernack, Paul M, Yang, Zhi-Yong, Pau, Maria G, Roederer, Mario, Koup, Richard A, Goudsmit, Jaap, Jahrling, Peter B, Nabel, Gary J
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459482/
https://ncbi.nlm.nih.gov/pubmed/16683867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030177
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