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Interferon Regulatory Factor 3-Dependent Pathways Are Critical for Control of Herpes Simplex Virus Type 1 Central Nervous System Infection

The initiation of the immune response at the cellular level relies on specific recognition molecules to rapidly signal viral infection via interferon (IFN) regulatory factor 3 (IRF-3)-dependent pathways. The absence of IRF-3 would be expected to render such pathways inoperative and thereby significa...

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Autori principali: Menachery, Vineet D., Pasieka, Tracy Jo, Leib, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937762/
https://ncbi.nlm.nih.gov/pubmed/20660188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00706-10
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