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Independent and Cooperative Roles of Adaptor Molecules in Proximal Signaling during FcɛRI-Mediated Mast Cell Activation
Activation through FcɛRI, a high-affinity IgE-binding receptor, is critical for mast cell function during allergy. The formation of a multimolecular proximal signaling complex nucleated by the adaptor molecules SLP-76 and LAT1 is required for activation through this receptor. Based on previous T-cel...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937553/ https://ncbi.nlm.nih.gov/pubmed/20606011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00305-10 |
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