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Independent and Cooperative Roles of Adaptor Molecules in Proximal Signaling during FcɛRI-Mediated Mast Cell Activation

Activation through FcɛRI, a high-affinity IgE-binding receptor, is critical for mast cell function during allergy. The formation of a multimolecular proximal signaling complex nucleated by the adaptor molecules SLP-76 and LAT1 is required for activation through this receptor. Based on previous T-cel...

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書誌詳細
主要な著者: Kambayashi, Taku, Okumura, Mariko, Baker, Rebecca G., Hsu, Chih-Jung, Baumgart, Tobias, Zhang, Weiguo, Koretzky, Gary A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937553/
https://ncbi.nlm.nih.gov/pubmed/20606011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00305-10
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