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CTCF Controls Expression and Chromatin Architecture of the Human Major Histocompatibility Complex Class II Locus

The major histocompatibility complex class II (MHC-II) locus includes a dense cluster of genes that function to initiate immune responses. Expression of insulator CCCTC binding factor (CTCF) was found to be required for expression of all MHC class II genes associated with antigen presentation. Ten C...

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Autors principals: Majumder, Parimal, Boss, Jeremy M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937552/
https://ncbi.nlm.nih.gov/pubmed/20584980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00327-10
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