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A super enhancer controls expression and chromatin architecture within the MHC class II locus
Super enhancers (SEs) play critical roles in cell type–specific gene regulation. The mechanisms by which such elements work are largely unknown. Two SEs termed DR/DQ-SE and XL9-SE are situated within the human MHC class II locus between the HLA-DRB1 and HLA-DQA1 genes and are highly enriched for dis...
Zapisane w:
| Wydane w: | J Exp Med |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Rockefeller University Press
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7041702/ https://ncbi.nlm.nih.gov/pubmed/31753848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190668 |
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