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CTCF Controls Expression and Chromatin Architecture of the Human Major Histocompatibility Complex Class II Locus

The major histocompatibility complex class II (MHC-II) locus includes a dense cluster of genes that function to initiate immune responses. Expression of insulator CCCTC binding factor (CTCF) was found to be required for expression of all MHC class II genes associated with antigen presentation. Ten C...

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Hlavní autoři: Majumder, Parimal, Boss, Jeremy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937552/
https://ncbi.nlm.nih.gov/pubmed/20584980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00327-10
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