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Adenovirus Vectors Block Human Immunodeficiency Virus–1 Replication in Human Alveolar Macrophages by Inhibition of the Long Terminal Repeat

Heterologous viruses may transactivate or suppress human immunodeficiency virus (HIV)–1 replication. An adenovirus type 5 gene transfer vector (Ad5) HIV-1 vaccine was recently evaluated in a clinical trial, without efficacy. In this context, it is relevant to ask what effect Ad vectors have on HIV-1...

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Détails bibliographiques
Auteurs principaux: Kaner, Robert J., Santiago, Francisco, Rahaghi, Franck, Michaels, Elizabeth, Moore, John P., Crystal, Ronald G.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937233/
https://ncbi.nlm.nih.gov/pubmed/19805482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0063OC
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