Adenovirus Vectors Block Human Immunodeficiency Virus–1 Replication in Human Alveolar Macrophages by Inhibition of the Long Terminal Repeat

Heterologous viruses may transactivate or suppress human immunodeficiency virus (HIV)–1 replication. An adenovirus type 5 gene transfer vector (Ad5) HIV-1 vaccine was recently evaluated in a clinical trial, without efficacy. In this context, it is relevant to ask what effect Ad vectors have on HIV-1...

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Detalhes bibliográficos
Main Authors: Kaner, Robert J., Santiago, Francisco, Rahaghi, Franck, Michaels, Elizabeth, Moore, John P., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937233/
https://ncbi.nlm.nih.gov/pubmed/19805482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0063OC
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