Chronic Interferon-Alpha Administration Disrupts Sleep Continuity and Depth in Patients with Hepatitis C: Association with Fatigue, Motor Slowing and Increased Evening Cortisol

BACKGROUND: Consequences of chronic exposure to cytokines of the innate immune system on sleep in humans and the association of cytokine-induced sleep alterations with behavior, motor performance and cortisol secretion are unknown. METHODS: Thirty-one patients with hepatitis C without pre-existing s...

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Main Authors: Raison, Charles L., Rye, David B., Woolwine, Bobbi J., Vogt, Gerald J., Bautista, Breanne M., Spivey, James R., Miller, Andrew H.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937202/
https://ncbi.nlm.nih.gov/pubmed/20537611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.04.019
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