Molecular Signatures of Peripheral Blood Mononuclear Cells during Chronic Interferon-alpha Treatment: Relationship with Depression and Fatigue

BACKGROUND: Interferon (IFN)-alpha treatment for infectious disease and cancer causes high rates of depression and fatigue, and has been used to investigate the impact of inflammatory cytokines on brain and behavior. However, little is known about the transcriptional impact of chronic IFN-alpha on i...

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Main Authors: Felger, Jennifer C., Cole, Steve W., Pace, Thaddeus W. W., Hu, Fang, Woolwine, Bobbi J., Doho, Gregory H., Raison, Charles L., Miller, Andrew H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433045/
https://ncbi.nlm.nih.gov/pubmed/22152193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033291711002868
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