Molecular Signatures of Peripheral Blood Mononuclear Cells during Chronic Interferon-alpha Treatment: Relationship with Depression and Fatigue

BACKGROUND: Interferon (IFN)-alpha treatment for infectious disease and cancer causes high rates of depression and fatigue, and has been used to investigate the impact of inflammatory cytokines on brain and behavior. However, little is known about the transcriptional impact of chronic IFN-alpha on i...

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Main Authors: Felger, Jennifer C., Cole, Steve W., Pace, Thaddeus W. W., Hu, Fang, Woolwine, Bobbi J., Doho, Gregory H., Raison, Charles L., Miller, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433045/
https://ncbi.nlm.nih.gov/pubmed/22152193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033291711002868
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