Activation of CNS Inflammatory Pathways by Interferon-alpha: Relationship to Monoamines and Depression

BACKGROUND: Interferon (IFN)-alpha has been used to study the effects of innate immune cytokines on the brain and behavior in humans. The degree to which peripheral administration of IFN-alpha accesses the brain and is associated with a central nervous system (CNS) inflammatory response is unknown....

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Main Authors: Raison, Charles L., Borisov, Andrey S., Majer, Matthias, Drake, Daniel F., Pagnoni, Giuseppe, Woolwine, Bobbi J., Vogt, Gerald J, Massung, Breanne, Miller, Andrew H.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655138/
https://ncbi.nlm.nih.gov/pubmed/18801471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.08.010
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