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Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo
The present study tested whether aging sensitizes hippocampal microglia to a pro-inflammatory challenge ex vivo. Hippocampal microglia from 3 and 24 mo old male F344 × BN F1 rats were exposed to LPS (0, 0.1, 1, 10 and 100 ng/ml) ex vivo. 2 h post-LPS challenge, gene expression of microglial activati...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937085/ https://ncbi.nlm.nih.gov/pubmed/20537730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.05.022 |
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