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Diminished circadian rhythms in hippocampal microglia may contribute to age-related neuroinflammatory sensitization

Aged animals exhibit diminished circadian rhythms, and both aging and circadian disruption sensitize neuroinflammatory responses. Microglia –the innate immune cell of the CNS – possess endogenous timekeeping mechanisms that regulate immune responses. Here, we explored whether aging is associated wit...

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Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Fonken, Laura K., Kitt, Meagan M., Gaudet, Andrew D., Barrientos, Ruth M., Watkins, Linda R., Maier, Steven F.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813798/
https://ncbi.nlm.nih.gov/pubmed/27568094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.07.019
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