Greater Glucocorticoid Receptor Activation in Hippocampus of Aged Rats Sensitizes Microglia

Healthy aging individuals are more likely to suffer profound memory impairments following an immune challenge than are younger adults. These challenges produce a brain inflammatory response that is exaggerated with age. Sensitized microglia found in the normal aging brain are responsible for this am...

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Bibliografiske detaljer
Udgivet i:Neurobiol Aging
Main Authors: Barrientos, Ruth M., Thompson, Vanessa M., Kitt, Meagan M., Amat, Jose, Hale, Matthew W., Frank, Matthew G., Crysdale, Nicole Y., Stamper, Christopher E., Hennessey, Patrick A., Watkins, Linda R., Spencer, Robert L., Lowry, Christopher A., Maier, Steven F.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346455/
https://ncbi.nlm.nih.gov/pubmed/25559333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.12.003
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