Greater Glucocorticoid Receptor Activation in Hippocampus of Aged Rats Sensitizes Microglia

Healthy aging individuals are more likely to suffer profound memory impairments following an immune challenge than are younger adults. These challenges produce a brain inflammatory response that is exaggerated with age. Sensitized microglia found in the normal aging brain are responsible for this am...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Barrientos, Ruth M., Thompson, Vanessa M., Kitt, Meagan M., Amat, Jose, Hale, Matthew W., Frank, Matthew G., Crysdale, Nicole Y., Stamper, Christopher E., Hennessey, Patrick A., Watkins, Linda R., Spencer, Robert L., Lowry, Christopher A., Maier, Steven F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346455/
https://ncbi.nlm.nih.gov/pubmed/25559333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.12.003
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