Alphavirus Replicon Particles Expressing TRP-2 Provide Potent Therapeutic Effect on Melanoma through Activation of Humoral and Cellular Immunity

BACKGROUND: Malignant melanoma is the deadliest form of skin cancer and is refractory to conventional chemotherapy and radiotherapy. Therefore alternative approaches to treat this disease, such as immunotherapy, are needed. Melanoma vaccine design has mainly focused on targeting CD8(+) T cells. Acti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Avogadri, Francesca, Merghoub, Taha, Maughan, Maureen F., Hirschhorn-Cymerman, Daniel, Morris, John, Ritter, Erika, Olmsted, Robert, Houghton, Alan N., Wolchok, Jedd D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937034/
https://ncbi.nlm.nih.gov/pubmed/20844763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012670
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados