Enhanced Long-Term Transduction and Multilineage Engraftment of Human Hematopoietic Stem Cells Transduced with Tyrosine-Modified Recombinant Adeno-Associated Virus Serotype 2

The search for the ideal stem cell gene therapy vector continues as recognized problems persist. Although recombinant adeno-associated virus serotype 2 (rAAV2) mediates gene transfer into hematopoietic stem cells, identified restrictions to transgene expression reduce overall efficiency. Studies hav...

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Autors principals: Kauss, M. Ariel, Smith, Laura J., Zhong, Li, Srivastava, Arun, Wong, K.K., Chatterjee, Saswati
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936497/
https://ncbi.nlm.nih.gov/pubmed/20486772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.016
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