Recombinant AAV2 transduction of primitive human hematopoietic stem cells capable of serial engraftment in immune-deficient mice

A recombinant AAV2 (rAAV2) vector encoding antisense RNA to HIV-1 transactivating region (TAR) was evaluated for transduction of human cord blood CD34(+)CD38(-) hematopoietic stem cells (HSC) capable of serial engraftment in nonobese diabetic (NOD)/severe combined immunodeficient (SCID) mice. Result...

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Bibliographische Detailangaben
Hauptverfasser: Santat, Leah, Paz, Helicia, Wong, Christie, Li, Lijing, Macer, James, Forman, Stephen, Wong, K. K., Chatterjee, Saswati
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182430/
https://ncbi.nlm.nih.gov/pubmed/16043711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502902102
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