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Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines

Adeno-associated virus (AAV)-based vectors have transformed into powerful elements of genetic medicine with proven therapeutic efficacy and a good safety profile. Over the years, efforts to transduce hematopoietic stem cells (HSCs) with AAV2 vectors have, however, been challenging. While there was e...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Chatterjee, Saswati, Sivanandam, Venkatesh, Wong, Kamehameha Kai-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232699/
https://ncbi.nlm.nih.gov/pubmed/32253938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2020.049
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