ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration

BACKGROUND AND PURPOSE: The epithelial sodium channel (ENaC) regulates airway mucosal hydration and mucus clearance. The lack of such regulation in cystic fibrosis patients leads to dessication of the airway lumen, resulting in mucostasis that establishes the environment for infections. Osmotic agen...

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Detalhes bibliográficos
Main Authors: Blé, F-X, Cannet, C, Collingwood, S, Danahay, H, Beckmann, N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936005/
https://ncbi.nlm.nih.gov/pubmed/20590595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00747.x
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