Microsomal prostaglandin E synthase-1 contributes to ischaemic excitotoxicity through prostaglandin E(2) EP(3) receptors

BACKGROUND AND PURPOSE: Although microsomal prostaglandin E synthase (mPGES)-1 is known to contribute to stroke injury, the underlying mechanisms remain poorly understood. This study examines the hypothesis that EP(3) receptors contribute to stroke injury as downstream effectors of mPGES-1 neurotoxi...

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Detalhes bibliográficos
Main Authors: Ikeda-Matsuo, Y, Tanji, H, Ota, A, Hirayama, Y, Uematsu, S, Akira, S, Sasaki, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers with Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935993/
https://ncbi.nlm.nih.gov/pubmed/20590584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00711.x
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