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CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content
Mutations in human CEP290 cause cilia-related disorders that range in severity from isolated blindness to perinatal lethality. Here, we describe a Chlamydomonas reinhardtii mutant in which most of the CEP290 gene is deleted. Immunoelectron microscopy indicated that CEP290 is located in the flagellar...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935561/ https://ncbi.nlm.nih.gov/pubmed/20819941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006105 |
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