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Kinetic Spectroscopy of Heme Hydration and Ligand Binding in Myoglobin and Isolated Hemoglobin Chains: An Optical Window into Heme Pocket Water Dynamics

The entry of a water molecule into the distal heme pocket of pentacoordinate heme proteins such as myoglobin and the α,β chains of hemoglobin can be detected by time-resolved spectroscopy in the heme visible bands after photolysis of the CO complex. Reviewing the evidence from spectrokinetic studies...

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Bibliografiske detaljer
Main Authors: Esquerra, Raymond M., López-Peña, Ignacio, Tipgunlakant, Pooncharas, Birukou, Ivan, Nguyen, Rosa L., Soman, Jayashree, Olson, John S., Kliger, David S., Goldbeck, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935257/
https://ncbi.nlm.nih.gov/pubmed/20668762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c003606b
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