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Water and ligand entry in myoglobin: Assessing the speed and extent of heme pocket hydration after CO photodissociation

A previously undescribed spectrokinetic assay for the entry of water into the distal heme pocket of wild-type and mutant myoglobins is presented. Nanosecond photolysis difference spectra were measured in the visible bands of sperm whale myoglobin as a function of distal pocket mutation and temperatu...

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Detalhes bibliográficos
Main Authors: Goldbeck, Robert A., Bhaskaran, Shyam, Ortega, Cheri, Mendoza, Juan L., Olson, John S., Soman, Jayashree, Kliger, David S., Esquerra, Raymond M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360539/
https://ncbi.nlm.nih.gov/pubmed/16432219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507840103
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