Over-expression of ST3Gal-I promotes mammary tumorigenesis

Changes in glycosylation are common in malignancy, and as almost all surface proteins are glycosylated, this can dramatically affect the behavior of tumor cells. In breast carcinomas, the O-linked glycans are frequently truncated, often as a result of premature sialylation. The sialyltransferase ST3...

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Détails bibliographiques
Auteurs principaux: Picco, Gianfranco, Julien, Sylvain, Brockhausen, Inka, Beatson, Richard, Antonopoulos, Aristotelis, Haslam, Stuart, Mandel, Ulla, Dell, Anne, Pinder, Sarah, Taylor-Papadimitriou, Joyce, Burchell, Joy
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934706/
https://ncbi.nlm.nih.gov/pubmed/20534593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwq085
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