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ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes

The precise glycosyltransferase enzymes that mediate selectin-ligand biosynthesis in human leukocytes are unknown. This knowledge is important because selectin-mediated cell tethering and rolling is a critical component of both normal immune response and various vascular disorders. We evaluated the...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Mondal, Nandini, Buffone, Alexander, Stolfa, Gino, Antonopoulos, Aristotelis, Lau, Joseph T. Y., Haslam, Stuart M., Dell, Anne, Neelamegham, Sriram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304113/
https://ncbi.nlm.nih.gov/pubmed/25498912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-588590
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