Over-expression of ST3Gal-I promotes mammary tumorigenesis

Changes in glycosylation are common in malignancy, and as almost all surface proteins are glycosylated, this can dramatically affect the behavior of tumor cells. In breast carcinomas, the O-linked glycans are frequently truncated, often as a result of premature sialylation. The sialyltransferase ST3...

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Autores principales: Picco, Gianfranco, Julien, Sylvain, Brockhausen, Inka, Beatson, Richard, Antonopoulos, Aristotelis, Haslam, Stuart, Mandel, Ulla, Dell, Anne, Pinder, Sarah, Taylor-Papadimitriou, Joyce, Burchell, Joy
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934706/
https://ncbi.nlm.nih.gov/pubmed/20534593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwq085
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