The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL

Aberrant glycosylation occurs in the majority of human cancers and changes in mucin-type O-glycosylation are key events that play a role in the induction of invasion and metastases. These changes generate novel cancer-specific glyco-antigens that can interact with cells of the immune system through...

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Publicat a:PLoS One
Autors principals: Beatson, Richard, Maurstad, Gjertrud, Picco, Gianfranco, Arulappu, Appitha, Coleman, Julia, Wandell, Hans H., Clausen, Henrik, Mandel, Ulla, Taylor-Papadimitriou, Joyce, Sletmoen, Marit, Burchell, Joy M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423978/
https://ncbi.nlm.nih.gov/pubmed/25951175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125994
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