p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101

Functional inactivation of the tumor susceptibility gene tsg101 in NIH 3T3 fibroblasts results in cellular transformation and the ability to form metastatic tumors in nude mice. The N-terminal region of tsg101 protein is structurally similar to the catalytic domain of ubiquitin-conjugating enzymes,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ruland, Jürgen, Sirard, Christian, Elia, Andrew, MacPherson, David, Wakeham, Andrew, Li, Limin, Luis de la Pompa, José, Cohen, Stanley N., Mak, Tak W.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC29347/
https://ncbi.nlm.nih.gov/pubmed/11172041
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires