p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101

Functional inactivation of the tumor susceptibility gene tsg101 in NIH 3T3 fibroblasts results in cellular transformation and the ability to form metastatic tumors in nude mice. The N-terminal region of tsg101 protein is structurally similar to the catalytic domain of ubiquitin-conjugating enzymes,...

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Detaylı Bibliyografya
Asıl Yazarlar: Ruland, Jürgen, Sirard, Christian, Elia, Andrew, MacPherson, David, Wakeham, Andrew, Li, Limin, Luis de la Pompa, José, Cohen, Stanley N., Mak, Tak W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC29347/
https://ncbi.nlm.nih.gov/pubmed/11172041
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