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Heparanase 2 Interacts with Heparan Sulfate with High Affinity and Inhibits Heparanase Activity
Heparanase activity is highly implicated in cell dissemination associated with tumor metastasis, angiogenesis, and inflammation. Heparanase expression is induced in many hematological and solid tumors, associated with poor prognosis. Heparanase homolog, termed heparanase 2 (Hpa2), was cloned based o...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934666/ https://ncbi.nlm.nih.gov/pubmed/20576607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116384 |
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