The CXC Chemokine-degrading Protease SpyCep of Streptococcus pyogenes Promotes Its Uptake into Endothelial Cells

Streptococcus pyogenes expresses the LPXTG motif-containing cell envelope serine protease SpyCep (also called ScpC, PrtS) that degrades and inactivates the major chemoattractant interleukin 8 (IL-8), thereby impairing host neutrophil recruitment. In this study, we identified a novel function of SpyC...

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Detalhes bibliográficos
Main Authors: Kaur, Simran Jeet, Nerlich, Andreas, Bergmann, Simone, Rohde, Manfred, Fulde, Marcus, Zähner, Dorothea, Hanski, Emanuel, Zinkernagel, Annelies, Nizet, Victor, Chhatwal, Gursharan S., Talay, Susanne R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934647/
https://ncbi.nlm.nih.gov/pubmed/20562101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098053
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