Angiopoietin-like Protein 3 Inhibits Lipoprotein Lipase Activity through Enhancing Its Cleavage by Proprotein Convertases

Lipoprotein lipase (LPL)-mediated lipolysis of triglycerides is the first and rate-limiting step in chylomicron/very low density lipoprotein clearance at the luminal surface of the capillaries. Angiopoietin-like protein 3 (ANGPTL3) is shown to inhibit LPL activity and plays important roles in modula...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Jun, Afroza, Huq, Rader, Daniel J., Jin, Weijun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934623/
https://ncbi.nlm.nih.gov/pubmed/20581395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144279
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