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Angiopoietin-like 4 promotes the intracellular cleavage of lipoprotein lipase by PCSK3/furin in adipocytes

Lipoprotein lipase (LPL) catalyzes the breakdown of circulating triglycerides in muscle and fat. LPL is inhibited by several proteins, including angiopoietin-like 4 (ANGPTL4), and may be cleaved by members of the proprotein convertase subtilisin/kexin (PCSK) family. Here, we aimed to investigate the...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Dijk, Wieneke, Ruppert, Philip M. M., Oost, Lynette J., Kersten, Sander
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130958/
https://ncbi.nlm.nih.gov/pubmed/30021841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002426
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