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Differential Dynamics of ATR-Mediated Checkpoint Regulators

The ATR-Chk1 checkpoint pathway is activated by UV-induced DNA lesions and replication stress. Little was known about the spatio and temporal behaviour of the proteins involved, and we, therefore, examined the behaviour of the ATRIP-ATR and Rad9-Rad1-Hus1 putative DNA damage sensor complexes and the...

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Detalles Bibliográficos
Main Authors: Warmerdam, Daniël O., Kanaar, Roland, Smits, Veronique A. J.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933903/
https://ncbi.nlm.nih.gov/pubmed/20847938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/319142
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