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Effect of Treatment of Sprague Dawley Rats with AVE7688, Enalapril, or Candoxatril on Diet-Induced Obesity

The objective of this study was to determine the effect of AVE7688, a drug that inhibits both angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) activity, on neural and vascular defects caused by diet induced obesity (DIO). Rats at 12 weeks of age were fed a standard or high fat die...

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Détails bibliographiques
Auteurs principaux: Davidson, Eric P., Coppey, Lawrence J., Dake, Brian, Yorek, Mark A.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933895/
https://ncbi.nlm.nih.gov/pubmed/20847891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/686952
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