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Treatment of Zucker diabetic fatty rats with AVE7688 improves vascular and neural dysfunction

AIM: Vasopeptidase inhibitors are drugs that inhibit angiotensin-converting enzyme and neutral endopeptidase (NEP). The latter is a protease that degrades vasoactive peptides and is increased in diabetes. We have previously shown that treating streptozotocin-induced diabetic rats, an animal model of...

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書誌詳細
主要な著者: Oltman, C. L., Davidson, E. P., Coppey, L. J., Kleinschmidt, T. L., Yorek, M. A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667677/
https://ncbi.nlm.nih.gov/pubmed/18564175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2008.00924.x
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