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Vasopeptidase Inhibitor Ilepatril (AVE7688) Prevents Obesity- and Diabetes-induced Neuropathy in C57Bl/6J Mice

Previously we demonstrated that inhibition of neutral endopeptidase (NEP), a protease that degrades vaso- and neuro-active peptides, and angiotensin converting enzyme (ACE) with a vasopeptidase inhibitor improves vascular and neural function in diabetic rat models. The purpose of this study was to d...

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Detalhes bibliográficos
Main Authors: Coppey, Lawrence, Davidson, Eric, Lu, Bao, Gerard, Craig, Yorek, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014404/
https://ncbi.nlm.nih.gov/pubmed/20849865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.09.008
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