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Effect of Treatment of Sprague Dawley Rats with AVE7688, Enalapril, or Candoxatril on Diet-Induced Obesity

The objective of this study was to determine the effect of AVE7688, a drug that inhibits both angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) activity, on neural and vascular defects caused by diet induced obesity (DIO). Rats at 12 weeks of age were fed a standard or high fat die...

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Bibliografiske detaljer
Main Authors: Davidson, Eric P., Coppey, Lawrence J., Dake, Brian, Yorek, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933895/
https://ncbi.nlm.nih.gov/pubmed/20847891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/686952
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