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The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?
Epithelial-to-mesenchymal transition (EMT) is a fundamental process in development and disease. Zinc-finger enhancer binding (ZEB) transcription factors (ZEB1 and ZEB2) are crucial EMT activators, whereas members of the miR-200 family induce epithelial differentiation. They are reciprocally linked i...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933868/ https://ncbi.nlm.nih.gov/pubmed/20706219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.117 |
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