Development of a novel tumor-targeted vascular disrupting agent activated by MT-MMPs

Vascular disrupting agents (VDA) offer a strategy to starve solid tumors of nutrients and oxygen concomitant with tumor shrinkage. Several VDAs have progressed into early clinical trials but their therapeutic value seems to be compromised by systemic toxicity. In this report, we describe the design...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Atkinson, Jennifer M, Falconer, Robert A, Edwards, Dylan R, Pennington, Caroline J, Siller, Catherine S, Shnyder, Steven D, Bibby, Michael C, Patterson, Laurence H, Loadman, Paul M, Gill, Jason H
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933508/
https://ncbi.nlm.nih.gov/pubmed/20663911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1440
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