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BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer
Breast cancer metastasis suppressor gene-1 (BRMS1) mRNA and protein expression are significantly decreased in non-small cell lung cancer (NSCLC) and this is a poor prognostic indicator. Given that the BRMS1 promoter region contains a promoter-associated CpG island (CGI) that encompasses the transcri...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933360/ https://ncbi.nlm.nih.gov/pubmed/20455258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2707 |
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