Učitavanje...

Lovastatin Inhibits VEGFR and AKT Activation: Synergistic Cytotoxicity in Combination with VEGFR Inhibitors

BACKGROUND: In a recent study, we demonstrated the ability of lovastatin, a potent inhibitor of mevalonate synthesis, to inhibit the function of the epidermal growth factor receptor (EGFR). Lovastatin attenuated ligand-induced receptor activation and downstream signaling through the PI3K/AKT pathway...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Zhao, Tong T., Trinh, Diane, Addison, Christina L., Dimitroulakos, Jim
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933231/
https://ncbi.nlm.nih.gov/pubmed/20838437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012563
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!