Generation of antisera to purified prions in lipid rafts

Prion diseases are fatal neurodegenerative disorders caused by prion proteins (PrP). Infectious prions accumulate in the brain through a template-mediated conformational conversion of endogenous PrP(C) into alternately folded PrP(Sc). Immunoassays toward pre-clinical detection of infectious PrP(Sc)...

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Bibliografiske detaljer
Main Authors: Hnasko, Robert, Serban, Ana V, Carlson, George, Prusiner, Stanley B, Stanker, Larry H
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933057/
https://ncbi.nlm.nih.gov/pubmed/20647769
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