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De novo generation of prion strains
Prions are self-replicating proteins that cause neurodegenerative disorders such as “mad cow” disease. These misprocessed protein conformations accumulate in the central nervous system, causing spongiform changes in the brain and eventually death. Since the inception of the protein-only hypothesis —...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924856/ https://ncbi.nlm.nih.gov/pubmed/21947062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro2650 |
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