Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of LAMBDA, BRCAPRO, Myriad II, and modified Couch models

CONTEXT: Models have been developed to predict the probability that a person carries a detectable germline mutation in the BRCA1 or BRCA2 genes. Their relative performance in a clinical setting is unclear. OBJECTIVE: To compare the performance characteristics of four BRCA1/BRCA2 gene mutation predic...

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Main Authors: Lindor, Noralane M., Lindor, Rachel A., Apicella, Carmel, Dowty, James G., Ashley, Amanda, Hunt, Katherine, Mincey, Betty A., Wilson, Marcia, Smith, M. Cathie, Hopper, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933048/
https://ncbi.nlm.nih.gov/pubmed/17636425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-007-9150-z
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